Drug Discovery Grid

Weighted-HR: An Improved Hierarchical Grid Resource Discovery

Grid computing environments include heterogeneous resources shared by a large number of computers to handle the data and process intensive applications. In these environments, the required resources must be accessible for Grid applications on demand, which makes the resource discovery as a critical service. In recent years, various techniques are proposed to index and discover the Grid resource...

A Graphical Workflow Modeler for Docking Process in Drug Discovery

A drug discovery process is aimed to find from a large set of molecules the candidate leads that have strong interaction with the target proteins. The process of drug discovery is characterized by its complexity in data and computation. A useful tool to simplify the handling of intensive data and complex algorithms is necessary for domain scientists to build proper drug discovery procedures, ca...

Drug Discovery Acceleration Using Digital Microfluidic Biochip Architecture and Computer-aided-design Flow

A Digital Microfluidic Biochip (DMFB) offers a promising platform for medical diagnostics, DNA sequencing, Polymerase Chain Reaction (PCR), and drug discovery and development. Conventional Drug discovery procedures require timely and costly manned experiments with a high degree of human errors with no guarantee of success. On the other hand, DMFB can be a great solution for miniaturization, int...

Using grid techniques for drug target identification.

The completion of the sequencing of the human genome has opened an unprecedented opportunity in the discovery of novel drug targets for disease therapy. However, one of the major challenges facing the drug discovery community is the expanding of data and the need of large-scale computational power in a collaborative environment. Grid techniques can present an architectural framework that aims t...

***Removed from the Issue*** Application of Cell-Based Assay Systems for the Early Screening of Human Drug Hepatotoxicity in the Discovery Phase of Drug Development